KMID : 0978920000010040034
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Korean Journal of Clinical Geriatrics 2000 Volume.1 No. 4 p.34 ~ p.41
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A 7Minute Screen for Korean Alzheimer¡¯s Disease-Validity&Reliablity
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Oh Byoung-Hoon
Lee Jung-Hyun Lee Byung-Ook An Suk-Kyoon Lee Pil-Goo Yoo Kae-Joon
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Abstract
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Backgroud: The early diagnosis of Alzheimer¡¯s disease enables prompt and proper treatment. Therefore, the necessity of a screening test for the early diagnosis of Alzheimer¡¯s disease cannot be overly emp¶ìsized. The ¡®7 minute screen¡± test developed by Paul S. Solomon shows high sensitivity in early Alzheimer¡¯s disease screening and has merits in being able to be performed within a relatively short period of time. This study had translated the ¡°7 minute screen¡± test adaptable for Koreans, and evaluated its capability as a standard tool for the screening of early Alzheimer¡¯s disease in aspects of the tests reliability and validity.
Methods: : The subject group consisted of 36 persons diagnosed with Alzheimer¡¯s disease and an age and education level matched group was determined as the control. The ¡°7 minute screen¡± Korean version test comprised of a Benton temporal orientation test, enhanced cued recall test, clock drawing test, and verb¿Ü fluency along with MMSE-K, CDR, BDRS, and GDS were implemented and evaluated. For measurements of interrater reliability, two test examiners simultaneously evaluated the results of the ¡°7 minute screen¡± and for measurements of test -retest reliability, re -evaluations were done 1 month later.
Results : The results of all 4 components of the ¡®7 minute screen¡± between the subject and the control groups showed statistically significant differences (p< .05). Also, evaluation of the contraction rate of Alzheimer¡¯s disease according to the scores of MMSE-K and ¡°7 minute screen¡± by receiver operating characteristic analysis showed a MMSE-K area under the ROC curve (AUC) value of 0.901 and a ¡°7 minute screen¡± AUC value of 0.814 resulting in no statistical significance (p=0.111). How-ever, the results of the high and low risk grou~ by the ¡°7 minute screen¡± had a 92% sensitivity, 37 % specificity, 62% positive predictive value, and an 88% negative predictive value. The interrater reliabÇÇty
was 0.97 and the test-retest reliability was 0.75. The average time needed in completing the ¡°7 minute screen¡± was statistical significant being 12 minutes 21 seconds in the subject group and 10 minutes 5 seconds in the control group (p<.05) .
Conclusion: The implementation of the ¡°7 minute screen¡± as a diagnostic tool for Alzheimer¡¯s disease has been verified, however, the validity of the test for its use in the Korean elderly is insufficient. Therefore, for the ¡°7 minute screen¡± to be a valuable tool for the screening of Alzheimer¡¯s disease in the Korean elderly, the components and standard values of the test needs to be m¡£ÀÌfied ac cor¶ìng to culture ar¶ì education in order to increase the tests specficity and validity.
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KEYWORD
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7 minute screen, Alzheimer¡¯s disease, Validity, Realiability
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